Vyvanse: Duration, Uses, Side Effects, and Everything You Need to Know

If you or someone you know has been prescribed Vyvanse, it's essential to understand how this medication works, its duration, potential side effects, and other crucial information. In this comprehensive guide, we'll cover everything you need to know about Vyvanse in a casual yet clear and easy-to-understand manner.


Attention Deficit Hyperactivity Disorder (ADHD) and Binge Eating Disorder (BED) are two conditions that can significantly impact a person's daily life. Vyvanse is a prescription medication used to manage these disorders, helping to improve focus, attention, and impulse control. In this article, we'll dive deep into the world of Vyvanse, exploring its uses, how long it lasts, potential side effects, and more.

What is Vyvanse?

Vyvanse is a medication that contains lisdexamfetamine, a prodrug that is converted into dextroamphetamine, a stimulant, once it enters the body. Lisdexamfetamine is inactive on its own, but after conversion, dextroamphetamine works to increase the levels of certain neurotransmitters in the brain, such as dopamine and norepinephrine. This action helps to improve focus, attention, and impulse control in individuals with ADHD, while also reducing binge eating episodes in those with BED.

How to Take Vyvanse

When it comes to taking Vyvanse, it's essential to follow your doctor's recommendations and the instructions on the prescription label. Generally, Vyvanse is taken once a day in the morning, either with or without food. It's crucial to take it in the morning because taking it later in the day may cause insomnia or difficulty falling asleep. Always take the medication at the same time each day for the best results and never take more than the prescribed dose.

Vyvanse: How Long Does It Last?

One of the most common questions people have about Vyvanse is, "how long does it last?" The answer varies depending on several factors, such as the individual's metabolism and the specific dose taken. However, on average, Vyvanse starts working within 1.5 hours after taking the dose and can last up to 14 hours. This long-lasting effect makes it a popular choice for managing ADHD symptoms throughout the day.

Detection of Vyvanse in the Body

Another common question is how long Vyvanse can be detected in the body. The detection time for Vyvanse depends on several factors, including the individual's metabolism, the dose taken, and the specific drug test used. On average, Vyvanse can be detected in the body for 2-3 days after the last dose. However, this timeframe may vary depending on the individual and the testing method.

Potential Side Effects and Risks of Vyvanse

As with any medication, there are potential side effects and risks associated with Vyvanse. Some common side effects include dry mouth, loss of appetite, weight loss, nausea, dizziness, and irritability. While these side effects may be mild and manageable, it's essential to be aware of the more severe side effects that can occur.

Serious side effects of Vyvanse include heart problems, such as increased heart rate, high blood pressure, and even heart attack or stroke. Additionally, Vyvanse can cause psychosis, which may manifest as hallucinations, delusions, or paranoia. Circulation problems, such as numbness, coldness, or changes in skin color in the fingers and toes, may also occur.

Vyvanse has the potential to be habit-forming, and misuse or abuse of the medication can lead to addiction or even overdose. It's crucial to take Vyvanse exactly as prescribed and never share the medication with others.

Drug Interactions and Contraindications

When taking Vyvanse, it's essential to be aware of potential drug interactions and contraindications. One significant interaction to be aware of is with monoamine oxidase inhibitors (MAOIs), a class of medications used to treat depression and other psychiatric disorders. Taking Vyvanse with an MAOI can cause a dangerous interaction known as serotonin syndrome, which can be life-threatening. Symptoms of serotonin syndrome include agitation, confusion, rapid heart rate, and high blood pressure. If you are taking an MAOI, you should not take Vyvanse and should consult your doctor about alternative treatments.

Other medications that may interact with Vyvanse include certain antidepressants, blood pressure medications, and medications used to treat cold or allergy symptoms. Always inform your doctor of all medications and supplements you are taking to avoid potential interactions.

What Vyvanse is NOT Approved For

While Vyvanse is an effective treatment for ADHD and BED, it's essential to understand that it is not approved for weight loss or obesity treatment. Although Vyvanse may cause weight loss as a side effect, using the medication solely for this purpose is not recommended and can be dangerous. Always follow your doctor's recommendations for the appropriate use of Vyvanse.


In conclusion, Vyvanse is a powerful medication that can help manage the symptoms of ADHD and BED when used as prescribed. By understanding how Vyvanse works, how long it lasts, and potential side effects and interactions, you can make informed decisions about your treatment plan. Always consult your doctor with any questions or concerns about Vyvanse, and never hesitate to reach out for support if you experience any adverse effects or have concerns about misuse or addiction.